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Will test combo of anti-CD20 MAb with Janssen/Pharmacyclics' Imbruvica
December 6, 2013
By: Gil Roth
President, Pharma & Biopharma Outsourcing Association
TG Therapeutics has begun a multi-center Phase II trial to evaluate the safety and efficacy of the combination of TG-1101 (ublituximab) and Imbruvica (ibrutinib) for patients with Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL). This will be the first clinical trial evaluating the combination of TG-1101, the company’s novel glycoengineered anti-CD20 monoclonal antibody, and ibrutinib, the oral Bruton Tyrosine Kinase (BTK) inhibitor which was recently granted approval by t...
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